Henry Cousins

Education

MPhil, Bioscience Enterprise, University of Cambridge, 2018

AB, Molecular and Cellular Biology, Harvard University, 2017

High-throughput mutagenesis analysis

Geometric learning for transcriptomics

Drug discovery and repurposing

Retrospective clinical studies

Cousins, H., Nayar, G., & Altman, R. (2024). Computational Approaches to Drug Repurposing: Methods, Challenges, and Opportunities. Annu Rev Biomed Data Sci. https://doi.org/10.1146/annurev-biodatasci-110123-025333
Cousins, H., Taryn, H., Guo, Y., Tzeng, K., Cong, L., & Altman, R. (2023). Gene set proximity analysis: expanding gene set enrichment analysis through learned geometric embeddings, with drug-repurposing applications in COVID-19. Bioinformatics, 39(1), btac735. https://doi.org/10.1093/bioinformatics/btac735
Cousins, H., Kline, A., Wang, C., Qu, Y., Wang, M., Altman, R., Luo, Y., & Cong, L. (2021). Integrative analysis of viral entry networks and clinical outcomes identifies a protective role for spironolactone in severe COVID-19. medRxiv. https://doi.org/10.1101/2022.07.02.22277
Wang, C., Dinesh, R., Qu, Y., Rustagi, A., Cousins, H., Zengel, J., Guo, Y., Hall, T., Beck, A., Tso, L., Erdemic, E., Tanudtanud, K., Ren, S., Tzeng, K., Wilk, A., Wang, M., Carette, J., Altman, R., Blish, C., & Cong, L. (2021). CRISPRa screening with real world evidence identifies potassium channels as neuronal entry factors and druggable targets for SARS-CoV-2. bioRxiv. https://doi.org/10.1101/2021.07.01